MAD1L1 and SYT6

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

MAD1L1

SYT6

Description mitotic arrest deficient 1 like 1 synaptotagmin 6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Adverse response to drug ( 30420678)
  • Age at first birth ( 34211149)
  • Age at first sexual intercourse ( 27089180 34211149)
  • Alcohol consumption (drinks per week) ( 30643258)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Anthropometric traits (multi-trait analysis) ( 30166351)
  • Anxiety ( 31906708)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 28115744 21926972 27329760)
  • Bitter alcoholic beverage consumption ( 31046077)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Coronary artery disease ( 29212778 33020668)
  • Dimensional psychopathology (Social) ( 29496196)
  • Disruptive behavior disorder and attention deficit hyperactivity disorder ( 33495439)
  • Gastroesophageal reflux disease ( 34187846 31527586)
  • General factor of neuroticism ( 30867560)
  • Gut microbiota relative abundance (Streptococcus) ( 33208821)
  • Hand grip strength ( 29691431)
  • Idiopathic pulmonary fibrosis ( 31710517)
  • Longevity ( 20834067)
  • Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
  • Myocardial infarction ( 33532862)
  • Number of sexual partners ( 30643258)
  • Platelet count ( 32888494)
  • Plateletcrit ( 32888494)
  • Prostate cancer ( 29892016)
  • Prostate cancer (advanced) ( 29892016)
  • Refractive error ( 32231278)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 28991256 29483656 22688191 30285260 23974872)
  • Schizophrenia or bipolar disorder ( 24280982)
  • Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486)
  • Sepsis (28-day mortality) ( 32592749)
  • Sleep duration (short sleep) ( 30846698)
  • Smoking initiation ( 33082346)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Superior frontal gyrus volume ( 31530798)
  • Superior temporal gyrus volume ( 31530798)
  • Systolic blood pressure ( 30578418)
  • Testicular germ cell tumor ( 28604728 28604732 23666239)
  • Vaginal microbiome composition (Shannon diversity index) ( 32723796)
Interacting Genes 79 interacting genes: AIMP2 ALOX5 AMOTL2 ANXA5 ATG5 BAG5 BIRC2 CAPN7 CCDC57 CCHCR1 CCND2 CDC37 CDK18 CHERP CHST12 COIL CWF19L2 FAM131C FAM90A1 FSCN1 FXR1 GAS8 GPKOW HAUS1 HDAC1 HDAC2 HOXA10 KIF9 LENG1 LGALSL LMO1 LMO3 LNX1 MAD2L1 MAX MFAP1 MLX NDC80 NEBL NEK2 NINL NONO NTAQ1 NXPH1 PIBF1 PIN4 PML PPP1R18 PRKAR1B PSMA1 RNF8 RPA3 S100P SIN3A SIN3B SPATA18 SPATA2 STAM SUPT5H SYT17 SYT6 TCAF1 TEX11 TEX33 TPM1 TPM3 TPR TRIM29 TSC22D3 TSGA10 TSHZ3 TTYH3 TUBGCP4 TULP4 UBC UBTF USP15 YJU2 ZSCAN32 30 interacting genes: APP BRCA1 CCDC136 CCDC57 CNTROB DVL3 FXR1 FXR2 GMCL1 GOLGA2 HMBOX1 HOOK2 KANK2 KCTD9 KIF24 KIFC3 KRT40 LMNA LZTS1 MAD1L1 MCC MTUS2 NRXN1 PRKCB TNIP1 TRIM27 TRIM32 TSGA10 ZBTB43 ZBTB8A
Entrez ID 8379 148281
HPRD ID 04065 09654
Ensembl ID ENSG00000002822 ENSG00000134207
Uniprot IDs Q9Y6D9 I6L9C3 Q5T7P8
PDB IDs 1GO4 4DZO
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?