NAT2 and APC

  • Number of citations of the paper that reports this interaction (PubMedID 25640309)
  • 8
  • Data Source:
  • BioGRID (two hybrid)

NAT2

APC

Description N-acetyltransferase 2 APC regulator of WNT signaling pathway
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Bladder cancer ( 24163127 20972438)
  • Blood metabolite levels ( 24816252)
  • Blood metabolite ratios ( 24816252)
  • Cholesterol, total ( 24097068 20686565)
  • Coronary artery disease ( 29212778 33020668)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Insulin resistance/response ( 25798622)
  • Iron status biomarkers (total iron binding capacity) ( 33536631)
  • Iron status biomarkers (transferrin levels) ( 25352340)
  • LDL cholesterol levels ( 32203549)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Liver injury in anti-tuberculosis drug treatment ( 31109976)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolic syndrome ( 31589552)
  • Metabolic traits ( 21886157)
  • Metabolite levels ( 23823483)
  • Myocardial infarction ( 33532862)
  • Night sleep phenotypes ( 27126917)
  • Paclitaxel-induced neuropathy ( 23776197)
  • Serum metabolite levels ( 33031748)
  • Total cholesterol levels ( 28334899 33339817)
  • Triglyceride levels ( 32203549 28334899 29403010 33339817 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 24097068 20686565)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
  • Urinary metabolites ( 26352407 21572414)
  • Urinary metabolites (H-NMR features) ( 24586186)
  • Youthful appearance (self-reported) ( 32339537)
Interacting Genes 18 interacting genes: APC APP AURKA BAG4 CDKN2A CDKN2C CLU ERBB2 FZR1 HMMR IGF1R MBD4 NAA10 NBN PALB2 PPM1D STK11 WT1 138 interacting genes: ACTN1 ADGRL1 AGFG1 AGR3 ANKRD17 ANP32B ANXA7 AP2B1 ARHGEF4 ASAP2 AXIN1 AXIN2 BAAT BUB1 BUB1B C4A CASC3 CCL5 CGNL1 COG4 COG5 CREBBP CSNK1A1 CSNK1E CTBP1 CTNNB1 CTSV CYP17A1 CYTH2 DIRAS3 DKK3 DLG3 DLGAP1 DST EPAS1 ERBIN EXPH5 FAM214A FANCC FBP1 FBXO30 FHOD1 FLNA GIGYF2 GOLGA2 GSK3B HGS HNRNPM HOXC6 HPCA HSPA5 HTRA2 IL24 ING5 IQGAP1 JUP KIAA1328 KIF5B KIFAP3 KRT13 KRT14 KRT15 KRT17 KRT23 KRT5 LAMA3 LAMA4 MACF1 MAN2A1 MAP2K1 MAPRE1 MAPRE2 MBD5 MCM3AP MKRN1 MT-ND4 MUC1 MYH10 MYH11 MYO6 NANS NAT2 NAV1 NAV2 NAV3 NCKAP5 NCKAP5L NEB NOSTRIN NUP153 NUP214 NUP42 NUP54 NUP58 NUP98 PDLIM2 PNISR POM121 POM121C PPP1R13B PPP2CA PPP2R5A PPP3R2 PRKACA PSMD1 PTPN13 RANBP9 RASA1 RBM4B RP1 RPS27 SCRIB SEC31A SETDB1 SIAH1 SMAD1 SMC3 SNRNP200 SPECC1L SPTBN1 SPTBN2 ST14 SYNE1 TAF1 TFAP2A TFF1 TGFB1 TMEFF1 TMOD1 TPR TRIM21 TRIM25 TSTD2 TUBA4A XPO1 YWHAQ ZNF106 ZNF510
Entrez ID 10 324
HPRD ID 02000 01439
Ensembl ID ENSG00000156006 ENSG00000134982
Uniprot IDs A4Z6T7 P11245 P25054 Q4LE70
PDB IDs 2PFR 1DEB 1EMU 1JPP 1M5I 1T08 1TH1 1V18 2RQU 3AU3 3NMW 3NMX 3NMZ 3QHE 3RL7 3RL8 3T7U 4G69 4YJE 4YJL 4YK6 5B6G 5IZ6 5IZ8 5IZ9 5IZA 5Z8H
Enriched GO Terms of Interacting Partners?
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