NAT2 and MBD4

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

NAT2

MBD4

Description N-acetyltransferase 2 methyl-CpG binding domain 4, DNA glycosylase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Bladder cancer ( 24163127 20972438)
  • Blood metabolite levels ( 24816252)
  • Blood metabolite ratios ( 24816252)
  • Cholesterol, total ( 24097068 20686565)
  • Coronary artery disease ( 29212778 33020668)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Insulin resistance/response ( 25798622)
  • Iron status biomarkers (total iron binding capacity) ( 33536631)
  • Iron status biomarkers (transferrin levels) ( 25352340)
  • LDL cholesterol levels ( 32203549)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Liver injury in anti-tuberculosis drug treatment ( 31109976)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolic syndrome ( 31589552)
  • Metabolic traits ( 21886157)
  • Metabolite levels ( 23823483)
  • Myocardial infarction ( 33532862)
  • Night sleep phenotypes ( 27126917)
  • Paclitaxel-induced neuropathy ( 23776197)
  • Serum metabolite levels ( 33031748)
  • Total cholesterol levels ( 28334899 33339817)
  • Triglyceride levels ( 32203549 28334899 29403010 33339817 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 24097068 20686565)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
  • Urinary metabolites ( 26352407 21572414)
  • Urinary metabolites (H-NMR features) ( 24586186)
  • Youthful appearance (self-reported) ( 32339537)
  • Diisocyanate-induced asthma ( 25918132)
  • Systemic sclerosis (anti-topoisomerase-positive) ( 29293537)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 18 interacting genes: APC APP AURKA BAG4 CDKN2A CDKN2C CLU ERBB2 FZR1 HMMR IGF1R MBD4 NAA10 NBN PALB2 PPM1D STK11 WT1 16 interacting genes: CDCA2 CSNK2B DNMT3B EPHB1 FADD FAS HDAC1 KDM1A MLH1 NAT2 SIN3A SUV39H1 TRIM27 TRIM55 TRIM63 UHRF1
Entrez ID 10 8930
HPRD ID 02000 04654
Ensembl ID ENSG00000156006 ENSG00000129071
Uniprot IDs A4Z6T7 P11245 O95243
PDB IDs 2PFR 2MOE 3IHO 4DK9 4E9E 4E9F 4E9G 4E9H 4EA4 4EA5 4LG7 4OFA 4OFE 4OFH 5CHZ 6VJW
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?