APC and MYH11

  • Number of citations of the paper that reports this interaction (PubMedID 20936779)
  • 88
  • Data Source:
  • BioGRID (two hybrid)

APC

MYH11

Description APC regulator of WNT signaling pathway myosin heavy chain 11
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cognitive function ( 25644384)
  • Coronary artery disease ( 29212778 33020668)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Haemorrhoidal disease ( 33888516)
  • Multiple myeloma (survival) ( 26198393)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)
  • PR interval ( 32439900)
  • Pulse pressure ( 27841878 30578418)
  • Resting heart rate ( 29769521 27798624)
  • Serum immune biomarker levels ( 32066700)
  • Serum uric acid levels in response to allopurinol in gout ( 25676789)
  • Skin aging measurement ( 31522824)
  • Waist-hip ratio ( 23966867)
Interacting Genes 138 interacting genes: ACTN1 ADGRL1 AGFG1 AGR3 ANKRD17 ANP32B ANXA7 AP2B1 ARHGEF4 ASAP2 AXIN1 AXIN2 BAAT BUB1 BUB1B C4A CASC3 CCL5 CGNL1 COG4 COG5 CREBBP CSNK1A1 CSNK1E CTBP1 CTNNB1 CTSV CYP17A1 CYTH2 DIRAS3 DKK3 DLG3 DLGAP1 DST EPAS1 ERBIN EXPH5 FAM214A FANCC FBP1 FBXO30 FHOD1 FLNA GIGYF2 GOLGA2 GSK3B HGS HNRNPM HOXC6 HPCA HSPA5 HTRA2 IL24 ING5 IQGAP1 JUP KIAA1328 KIF5B KIFAP3 KRT13 KRT14 KRT15 KRT17 KRT23 KRT5 LAMA3 LAMA4 MACF1 MAN2A1 MAP2K1 MAPRE1 MAPRE2 MBD5 MCM3AP MKRN1 MT-ND4 MUC1 MYH10 MYH11 MYO6 NANS NAT2 NAV1 NAV2 NAV3 NCKAP5 NCKAP5L NEB NOSTRIN NUP153 NUP214 NUP42 NUP54 NUP58 NUP98 PDLIM2 PNISR POM121 POM121C PPP1R13B PPP2CA PPP2R5A PPP3R2 PRKACA PSMD1 PTPN13 RANBP9 RASA1 RBM4B RP1 RPS27 SCRIB SEC31A SETDB1 SIAH1 SMAD1 SMC3 SNRNP200 SPECC1L SPTBN1 SPTBN2 ST14 SYNE1 TAF1 TFAP2A TFF1 TGFB1 TMEFF1 TMOD1 TPR TRIM21 TRIM25 TSTD2 TUBA4A XPO1 YWHAQ ZNF106 ZNF510 4 interacting genes: APC DAXX GRB2 MAPKAPK5
Entrez ID 324 4629
HPRD ID 01439 01174
Ensembl ID ENSG00000134982 ENSG00000133392
Uniprot IDs P25054 Q4LE70 A0A024QZJ4 A0A024QZJ6 P35749
PDB IDs 1DEB 1EMU 1JPP 1M5I 1T08 1TH1 1V18 2RQU 3AU3 3NMW 3NMX 3NMZ 3QHE 3RL7 3RL8 3T7U 4G69 4YJE 4YJL 4YK6 5B6G 5IZ6 5IZ8 5IZ9 5IZA 5Z8H
Enriched GO Terms of Interacting Partners?
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