NAT2 and STK11

  • Number of citations of the paper that reports this interaction (PubMedID 25640309)
  • 8
  • Data Source:
  • BioGRID (two hybrid)

NAT2

STK11

Description N-acetyltransferase 2 serine/threonine kinase 11
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Bladder cancer ( 24163127 20972438)
  • Blood metabolite levels ( 24816252)
  • Blood metabolite ratios ( 24816252)
  • Cholesterol, total ( 24097068 20686565)
  • Coronary artery disease ( 29212778 33020668)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Insulin resistance/response ( 25798622)
  • Iron status biomarkers (total iron binding capacity) ( 33536631)
  • Iron status biomarkers (transferrin levels) ( 25352340)
  • LDL cholesterol levels ( 32203549)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Liver injury in anti-tuberculosis drug treatment ( 31109976)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolic syndrome ( 31589552)
  • Metabolic traits ( 21886157)
  • Metabolite levels ( 23823483)
  • Myocardial infarction ( 33532862)
  • Night sleep phenotypes ( 27126917)
  • Paclitaxel-induced neuropathy ( 23776197)
  • Serum metabolite levels ( 33031748)
  • Total cholesterol levels ( 28334899 33339817)
  • Triglyceride levels ( 32203549 28334899 29403010 33339817 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 24097068 20686565)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
  • Urinary metabolites ( 26352407 21572414)
  • Urinary metabolites (H-NMR features) ( 24586186)
  • Youthful appearance (self-reported) ( 32339537)
  • Asthma (childhood onset) ( 31036433)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Distal/Left-sided colorectal cancer ( 33632709)
  • Inflammatory bowel disease ( 28067908)
  • Lymphocyte counts ( 32888494 27863252)
  • Lymphocyte percentage of white cells ( 32888494)
  • Neutrophil percentage of white cells ( 32888494)
  • PR interval ( 32439900)
  • Psychosis in Alzheimer's disease ( 22005930)
Interacting Genes 18 interacting genes: APC APP AURKA BAG4 CDKN2A CDKN2C CLU ERBB2 FZR1 HMMR IGF1R MBD4 NAA10 NBN PALB2 PPM1D STK11 WT1 140 interacting genes: ABCB5 ADIPOR1 AKT1 ALDOB ANP32B APP ARAF ARG2 ARNT ATM AURKA BAP1 BCAS3 BECN1 BRAF CAB39 CALM2 CBLC CCDC180 CCND2 CCNE1 CD44 CDC14B CDC37 CDK4 CDK6 CDKN2A CDKN2B CDKN2C CFL2 CRY2 CTSB CYLC2 CYP17A1 D2HGDH DACH1 EEF1A2 EPHA2 ERBB2 ERLEC1 ETV4 FAIM2 FAM98B FBP1 FBP2 FGFR4 FZR1 GLIS2 GNPDA1 GRM1 HERC2 HGF HIF1A HRAS IGFBP3 KAT2A KDELR2 KLK7 LATS2 LEF1 LYPD3 MADCAM1 MAP2K1 MAP2K3 MAP2K5 MAP2K6 MAP3K5 MAPK14 MAPK3 MAPRE1 MARK1 MARK2 MARK4 MDM2 MET MOB4 MOCS2 MT-ND2 MYC NANS NAT2 NF2 PARD3 PDGFRA PDXP PHF23 PIK3CA PLD3 PPP2CB PPP6R1 PRKAA1 PRKAA2 PRKACA PRSS50 PTEN RASA1 RASSF1 RHOBTB2 RPS6KA3 RPS6KA5 RPS6KB1 S100A14 SEPTIN9 SERPINB5 SH3GL1 SIK1 SIRT1 SMAD1 SMARCA4 SNRK SOX4 SPDEF ST14 STK11IP STK24 STRADA STRADB STX17 TBC1D23 TDRD7 TEAD2 TERT THOP1 THRSP TNFRSF1A TNIP2 TP53 TRIM25 TRMO TSG101 TUBA1A TUBB4A UBE2D2 VPS72 WT1 XPA YWHAG ZNF189 ZNF195 ZNF510
Entrez ID 10 6794
HPRD ID 02000 03740
Ensembl ID ENSG00000156006 ENSG00000118046
Uniprot IDs A4Z6T7 P11245 A0A0S2Z4D1 Q15831
PDB IDs 2PFR 2WTK 4ZDR 5WXN
Enriched GO Terms of Interacting Partners?
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