ZBTB5 and ZBTB7B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZBTB5	ZBTB7B
Description		zinc finger and BTB domain containing 5	zinc finger and BTB domain containing 7B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus	Negative Regulation Of Transcription By RNA Polymerase II NK T Cell Differentiation Transcription By RNA Polymerase II Ectoderm Development Lactation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Histone Deacetylation Response To Insulin Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Negative Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of NK T Cell Proliferation Regulation Of Transcription Involved In Cell Fate Commitment Interleukin-17 Secretion Positive Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis Adaptive Thermogenesis Negative Regulation Of T-helper 17 Cell Differentiation Positive Regulation Of SREBP Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Basal cell carcinoma ( 31174203) Bipolar disorder ( 31043756) Birth weight ( 27680694) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807) Keratinocyte cancer (MTAG) ( 31174203) Multiple sclerosis ( 31604244) Prostate cancer ( 23535732) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		8 interacting genes: CCDC85B DCX JADE2 PPARG PTPN5 ST3GAL3 SWAP70 ZBTB7B	19 interacting genes: BCL6 CRBN EP300 GRAP2 GRB2 IMP4 KPNA2 MORF4L2 NCK2 NDN PIN1 RELA RPL9 SH3KBP1 SH3YL1 SORBS3 SYTL4 ZBTB5 ZNF277
Entrez ID		9925	51043
HPRD ID		08829	09625
Ensembl ID		ENSG00000168795	ENSG00000160685
Uniprot IDs		O15062 Q5T942	O15156
PDB IDs
Enriched GO Terms of Interacting Partners?
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