ZBTB7B and MORF4L2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZBTB7B	MORF4L2
Description		zinc finger and BTB domain containing 7B	mortality factor 4 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Plasma Membrane NuA4 Histone Acetyltransferase Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II NK T Cell Differentiation Transcription By RNA Polymerase II Ectoderm Development Lactation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Histone Deacetylation Response To Insulin Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Negative Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of NK T Cell Proliferation Regulation Of Transcription Involved In Cell Fate Commitment Interleukin-17 Secretion Positive Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis Adaptive Thermogenesis Negative Regulation Of T-helper 17 Cell Differentiation Positive Regulation Of SREBP Signaling Pathway	DNA Repair Chromatin Silencing Histone Acetylation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Striated Muscle Cell Differentiation
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Basal cell carcinoma ( 31174203) Bipolar disorder ( 31043756) Birth weight ( 27680694) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807) Keratinocyte cancer (MTAG) ( 31174203) Multiple sclerosis ( 31604244) Prostate cancer ( 23535732) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		19 interacting genes: BCL6 CRBN EP300 GRAP2 GRB2 IMP4 KPNA2 MORF4L2 NCK2 NDN PIN1 RELA RPL9 SH3KBP1 SH3YL1 SORBS3 SYTL4 ZBTB5 ZNF277	29 interacting genes: BEND7 CDR2 CEP55 DDIT4L FAM9B GLA GOLGA2 GRAMD2B HDAC1 IKZF1 KLHL3 L3MBTL3 LZTS2 MRFAP1 MRFAP1L1 MRGBP PHC2 PNMA2 RB1 SIN3A THAP1 TLE1 TLE5 TNIP1 TNNT2 ZBTB10 ZBTB14 ZBTB43 ZBTB7B
Entrez ID		51043	9643
HPRD ID		09625	02326
Ensembl ID		ENSG00000160685	ENSG00000123562
Uniprot IDs		O15156	Q15014
PDB IDs
Enriched GO Terms of Interacting Partners?
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