ZBTB7B and ZNF277

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		ZBTB7B	ZNF277
Description		zinc finger and BTB domain containing 7B	zinc finger protein 277
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II NK T Cell Differentiation Transcription By RNA Polymerase II Ectoderm Development Lactation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Histone Deacetylation Response To Insulin Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Negative Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of NK T Cell Proliferation Regulation Of Transcription Involved In Cell Fate Commitment Interleukin-17 Secretion Positive Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis Adaptive Thermogenesis Negative Regulation Of T-helper 17 Cell Differentiation Positive Regulation Of SREBP Signaling Pathway	Cellular Response To Hydrogen Peroxide Regulation Of Cellular Senescence
Pathways
Drugs
Diseases
GWAS		Basal cell carcinoma ( 31174203) Bipolar disorder ( 31043756) Birth weight ( 27680694) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807) Keratinocyte cancer (MTAG) ( 31174203) Multiple sclerosis ( 31604244) Prostate cancer ( 23535732) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Breast size ( 22747683) Early-onset Parkinson's disease ( 28256260)
Interacting Genes		19 interacting genes: BCL6 CRBN EP300 GRAP2 GRB2 IMP4 KPNA2 MORF4L2 NCK2 NDN PIN1 RELA RPL9 SH3KBP1 SH3YL1 SORBS3 SYTL4 ZBTB5 ZNF277	7 interacting genes: COIL DDB1 GNGT1 MBD3 NUTM1 ZBTB7B ZNF768
Entrez ID		51043	11179
HPRD ID		09625	05680
Ensembl ID		ENSG00000160685	ENSG00000198839
Uniprot IDs		O15156	Q9NRM2
PDB IDs
Enriched GO Terms of Interacting Partners?
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