UBE3C and TLK1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		UBE3C	TLK1
Description		ubiquitin protein ligase E3C	tousled like kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus	Nucleus Nucleoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Conjugating Enzyme Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process	Regulation Of Chromatin Assembly Or Disassembly Chromatin Organization Protein Phosphorylation Intracellular Protein Transport Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Peptidyl-serine Phosphorylation Intracellular Signal Transduction
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 25673413) Language impairment in frontotemporal lobe dementia ( 29724592) Quantitative traits ( 19197348) Response to citalopram treatment ( 19846067) Type 2 diabetes ( 30054458)	Health literacy ( 31250787) Menopause (age at onset) ( 22267201 26414677) Platelet distribution width ( 27863252)
Interacting Genes		12 interacting genes: APP CAND2 CCNB1 GOLGA2 MTA2 PSMC5 PSMD2 TLK1 UBE2D1 UBE2D2 UBE2D3 UBE2L3	15 interacting genes: ASF1A ASF1B AURKA CHEK1 H1-1 LUZP4 MBP NBN PTPN11 RAD9A SNAP23 TLK2 TPM3 UBE3C YWHAE
Entrez ID		9690	9874
HPRD ID		15604	12232
Ensembl ID		ENSG00000009335	ENSG00000198586
Uniprot IDs		Q15386	Q9UKI8
PDB IDs
Enriched GO Terms of Interacting Partners?
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