UBE3C and CAND2

Number of citations of the paper that reports this interaction (PubMedID 12692129)
6

Data Source:
HPRD (in vivo, in vitro)

		UBE3C	CAND2
Description		ubiquitin protein ligase E3C	cullin associated and neddylation dissociated 2 (putative)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus	Nucleus Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding TBP-class Protein Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process	SCF Complex Assembly Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 25673413) Language impairment in frontotemporal lobe dementia ( 29724592) Quantitative traits ( 19197348) Response to citalopram treatment ( 19846067) Type 2 diabetes ( 30054458)	Atrial fibrillation ( 30061737 29892015) Creatine kinase levels ( 29403010) P wave duration ( 28794112) Waist circumference adjusted for body mass index ( 28552196) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		12 interacting genes: APP CAND2 CCNB1 GOLGA2 MTA2 PSMC5 PSMD2 TLK1 UBE2D1 UBE2D2 UBE2D3 UBE2L3	6 interacting genes: CNOT3 GLP1R MRPS25 RBX1 TBP UBE3C
Entrez ID		9690	23066
HPRD ID		15604	19120
Ensembl ID		ENSG00000009335	ENSG00000144712
Uniprot IDs		Q15386	O75155
PDB IDs
Enriched GO Terms of Interacting Partners?
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