TLK1 and ASF1A

Number of citations of the paper that reports this interaction (PubMedID 11470414)
74

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		TLK1	ASF1A
Description		tousled like kinase 1	anti-silencing function 1A histone chaperone
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Regulation Of Chromatin Assembly Or Disassembly Chromatin Organization Protein Phosphorylation Intracellular Protein Transport Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Peptidyl-serine Phosphorylation Intracellular Signal Transduction	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation
Pathways			Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Health literacy ( 31250787) Menopause (age at onset) ( 22267201 26414677) Platelet distribution width ( 27863252)	Multiple sclerosis ( 31604244) QT interval ( 19305408)
Interacting Genes		15 interacting genes: ASF1A ASF1B AURKA CHEK1 H1-1 LUZP4 MBP NBN PTPN11 RAD9A SNAP23 TLK2 TPM3 UBE3C YWHAE	22 interacting genes: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3-3A H3-4 H3C3 H3C6 H4-16 H4C13 H4C6 HIRA HTATIP2 PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17
Entrez ID		9874	25842
HPRD ID		12232	16459
Ensembl ID		ENSG00000198586	ENSG00000111875
Uniprot IDs		Q9UKI8	Q9Y294
PDB IDs			1TEY 2I32 2IIJ 2IO5 3AAD 5C3I 6F0F 6F0G 6F0H
Enriched GO Terms of Interacting Partners?
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