RIN1 and RRAS2

Number of citations of the paper that reports this interaction (PubMedID 19060904)
283

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid, in vivo)

		RIN1	RRAS2
Description		Ras and Rab interactor 1	RAS related 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Dendrite Neuronal Cell Body	Endoplasmic Reticulum Plasma Membrane Focal Adhesion Membrane Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Ras GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Endocytosis Signal Transduction Memory Associative Learning Negative Regulation Of Synaptic Plasticity Positive Regulation Of GTPase Activity	Osteoblast Differentiation Ras Protein Signal Transduction Positive Regulation Of Cell Migration Regulation Of Neuron Death
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Alzheimer's disease (cognitive decline) ( 23535033) Height ( 31562340) Mitochondrial DNA levels ( 25240745) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Multiple sclerosis ( 31604244) Vitamin D levels ( 25208829)
Interacting Genes		19 interacting genes: ABL1 ABL2 AFDN ANKS1B CALCOCO2 EGFR ERBB2 ERBB3 HRAS KRTAP13-1 LZTS2 MTDH RAB5A RAB5B RALGDS RRAS2 YWHAB YWHAE YWHAZ	29 interacting genes: ACVR1 AFDN AHSG ARAF ARHGEF2 BMPR1B CREB3 FNTB LGALS4 PAWR PGGT1B PIK3R1 PTPN1 RABAC1 RAF1 RALGDS RAPGEF1 RAPGEF3 RAPGEF4 RASGRF1 RASIP1 RASSF5 RIN1 SMAD3 SMAD4 SMURF2 TRAF2 TRAF3 XRCC6
Entrez ID		9610	22800
HPRD ID		05813	02518
Ensembl ID		ENSG00000174791	ENSG00000133818
Uniprot IDs		A0A0S2Z4U0 Q13671	P62070
PDB IDs			2ERY
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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