RRAS2 and RASSF5

Number of citations of the paper that reports this interaction (PubMedID 11857081)
64

Data Source:
HPRD (in vitro)

		RRAS2	RASSF5
Description		RAS related 2	Ras association domain family member 5
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GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Focal Adhesion Membrane Extracellular Exosome	Nucleus Cytoplasm Microtubule
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Binding Ras GTPase Binding Metal Ion Binding
	Biological Process	Osteoblast Differentiation Ras Protein Signal Transduction Positive Regulation Of Cell Migration Regulation Of Neuron Death	Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Height ( 31562340) Mitochondrial DNA levels ( 25240745) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Multiple sclerosis ( 31604244) Vitamin D levels ( 25208829)	Inflammatory bowel disease ( 23128233) Late-onset Alzheimer's disease ( 27770636) Neurofibrillary tangles ( 25188341)
Interacting Genes		29 interacting genes: ACVR1 AFDN AHSG ARAF ARHGEF2 BMPR1B CREB3 FNTB LGALS4 PAWR PGGT1B PIK3R1 PTPN1 RABAC1 RAF1 RALGDS RAPGEF1 RAPGEF3 RAPGEF4 RASGRF1 RASIP1 RASSF5 RIN1 SMAD3 SMAD4 SMURF2 TRAF2 TRAF3 XRCC6	30 interacting genes: ADH6 AMOTL2 APPBP2 BTRC HRAS ITCH KRAS KRT40 KRTAP4-2 LSM7 MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 VPS28
Entrez ID		22800	83593
HPRD ID		02518	06117
Ensembl ID		ENSG00000133818	ENSG00000266094
Uniprot IDs		P62070	A8K5F3 Q8WWW0
PDB IDs		2ERY	4LGD 4OH8
Enriched GO Terms of Interacting Partners?
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