LITAF and PLOD2

		LITAF	PLOD2
Description		lipopolysaccharide induced TNF factor	procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Intracellular Membrane-bounded Organelle Cytoplasmic Side Of Early Endosome Membrane Cytoplasmic Side Of Late Endosome Membrane Cytoplasmic Side Of Lysosomal Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding WW Domain Binding	Iron Ion Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity
	Biological Process	Regulation Of Cytokine Production Regulation Of Transcription By RNA Polymerase II Aging Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide Negative Regulation Of NIK/NF-kappaB Signaling	Response To Hypoxia Cellular Protein Modification Process Protein O-linked Glycosylation Peptidyl-lysine Hydroxylation Hydroxylysine Biosynthetic Process Oxidation-reduction Process
Pathways			Collagen biosynthesis and modifying enzymes
Drugs			Vitamin C
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy	Bruck syndrome
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Colorectal or endometrial cancer ( 26621817) Crohn's disease ( 28067908) Gallstone disease ( 30504769) Heel bone mineral density ( 30598549) Inflammatory bowel disease ( 28067908 23128233) QT interval ( 23166209 30679814 29213071 24952745 19305408 19305409) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)	Height ( 31562340) Obesity-related traits ( 23251661) Squamous cell lung carcinoma ( 28604730) Zinc levels ( 26025379)
Interacting Genes		15 interacting genes: ATXN1 BAG3 CALCOCO2 COMT HGS ITCH NEDD4 OPTN PLOD2 RADIL REEP6 SMAD2 STAM2 STAT6 UBQLN1	6 interacting genes: CENPF CLSTN2 LITAF LYPLA1 NUCB1 WWTR1
Entrez ID		9516	5352
HPRD ID		10354	03519
Ensembl ID		ENSG00000189067	ENSG00000152952
Uniprot IDs		Q99732	O00469
PDB IDs
Enriched GO Terms of Interacting Partners?
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