LITAF and REEP6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		LITAF	REEP6
Description		lipopolysaccharide induced TNF factor	receptor accessory protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Intracellular Membrane-bounded Organelle Cytoplasmic Side Of Early Endosome Membrane Cytoplasmic Side Of Late Endosome Membrane Cytoplasmic Side Of Lysosomal Membrane	Photoreceptor Inner Segment Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Clathrin-coated Vesicle Membrane Rod Spherule Apical Part Of Cell
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding WW Domain Binding	Protein Binding
	Biological Process	Regulation Of Cytokine Production Regulation Of Transcription By RNA Polymerase II Aging Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide Negative Regulation Of NIK/NF-kappaB Signaling	Regulation Of Intracellular Transport Detection Of Light Stimulus Involved In Visual Perception
Pathways			Olfactory Signaling Pathway
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Colorectal or endometrial cancer ( 26621817) Crohn's disease ( 28067908) Gallstone disease ( 30504769) Heel bone mineral density ( 30598549) Inflammatory bowel disease ( 28067908 23128233) QT interval ( 23166209 30679814 29213071 24952745 19305408 19305409) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
Interacting Genes		15 interacting genes: ATXN1 BAG3 CALCOCO2 COMT HGS ITCH NEDD4 OPTN PLOD2 RADIL REEP6 SMAD2 STAM2 STAT6 UBQLN1	20 interacting genes: ADAT3 COQ8A FAM160A2 HMBOX1 IZUMO4 LITAF LMNA NDRG4 PTPN9 RPS20 SCAMP4 SDCBP SNX1 SNX15 SPG21 TMEM259 TNS2 TXN2 ZFYVE21 ZNF554
Entrez ID		9516	92840
HPRD ID		10354	16629
Ensembl ID		ENSG00000189067	ENSG00000115255
Uniprot IDs		Q99732	A0A1L5BXV2 Q96HR9
PDB IDs
Enriched GO Terms of Interacting Partners?
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