FXR2 and SYTL4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FXR2	SYTL4
Description		FMR1 autosomal homolog 2	synaptotagmin like 4
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Axon Growth Cone Ribonucleoprotein Granule Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Dendritic Spine Dendritic Spine Neck Presynapse Dendritic Filopodium	Endosome Plasma Membrane Extrinsic Component Of Membrane Transport Vesicle Membrane Platelet Alpha Granule Membrane Exocytic Vesicle
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity	Protein Binding Phospholipid Binding Rab GTPase Binding Neurexin Family Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Negative Regulation Of Translation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Positive Regulation Of Response To DNA Damage Stimulus	Plasma Membrane Repair Platelet Degranulation Intracellular Protein Transport Exocytosis Lysosome Localization Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion Positive Regulation Of Protein Secretion Multivesicular Body Sorting Pathway Regulation Of Plasma Membrane Repair
Pathways			Platelet degranulation
Drugs			Insulin Human Insulin Pork
Diseases
GWAS		Atrial fibrillation ( 30061737) IgM levels ( 23118916) Sex hormone-binding globulin levels ( 22675492)	Lean body mass ( 28552196)
Interacting Genes		101 interacting genes: AKAP9 AMOTL2 AP1M1 AP2M1 ARL6IP1 BAZ2B BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CAMK2D CBS CCDC33 CCDC85B CDKL3 CEP44 CEP55 COIL CYFIP1 CYFIP2 DDX17 DMRTB1 DPPA2 DYNLT1 EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GKAP1 GTSE1 HMBOX1 HNRNPC KCNRG KCTD4 KIAA1217 KIF1A KIF2A KRT20 KXD1 LASP1 LCMT1 LCP2 LDOC1 MAPRE3 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MRPL43 NCK2 NDEL1 NDN NECAB2 NIF3L1 NME1 NONO NT5C2 PAF1 PAICS PCBD1 PCM1 PIM1 POM121 PRAM1 PRC1 PSME3 PTS RABAC1 RALYL RBBP8 RBM14 RBMX RBPMS RPIA RTN3 RTN4 SCEL SNAP23 SRPK2 SYT6 SYTL4 TBC1D22B THAP1 TNNT1 TRAF2 TRIM23 TRIM29 TRIM37 TSC22D4 YES1 ZBTB22 ZBTB8A ZMAT2 ZNF451 ZNRD2 ZSCAN1	12 interacting genes: CCDC85B CEP70 FXR2 HMG20A INS RAB27A RAB27B RAB3A RAB8A STX1A STXBP1 ZBTB7B
Entrez ID		9513	94121
HPRD ID		05629	06735
Ensembl ID		ENSG00000129245	ENSG00000102362
Uniprot IDs		P51116	A0A024RCF8 A8K973 B2R7R4 Q71SF7 Q96C24
PDB IDs		3H8Z	2CSZ 3FDW 5X6T
Enriched GO Terms of Interacting Partners?
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