FXR2 and C1orf35

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FXR2	C1orf35
Description		FMR1 autosomal homolog 2	chromosome 1 open reading frame 35
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Axon Growth Cone Ribonucleoprotein Granule Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Dendritic Spine Dendritic Spine Neck Presynapse Dendritic Filopodium	Extracellular Region Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity	RNA Binding Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Negative Regulation Of Translation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Positive Regulation Of Response To DNA Damage Stimulus	Neutrophil Degranulation
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737) IgM levels ( 23118916) Sex hormone-binding globulin levels ( 22675492)
Interacting Genes		101 interacting genes: AKAP9 AMOTL2 AP1M1 AP2M1 ARL6IP1 BAZ2B BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CAMK2D CBS CCDC33 CCDC85B CDKL3 CEP44 CEP55 COIL CYFIP1 CYFIP2 DDX17 DMRTB1 DPPA2 DYNLT1 EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GKAP1 GTSE1 HMBOX1 HNRNPC KCNRG KCTD4 KIAA1217 KIF1A KIF2A KRT20 KXD1 LASP1 LCMT1 LCP2 LDOC1 MAPRE3 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MRPL43 NCK2 NDEL1 NDN NECAB2 NIF3L1 NME1 NONO NT5C2 PAF1 PAICS PCBD1 PCM1 PIM1 POM121 PRAM1 PRC1 PSME3 PTS RABAC1 RALYL RBBP8 RBM14 RBMX RBPMS RPIA RTN3 RTN4 SCEL SNAP23 SRPK2 SYT6 SYTL4 TBC1D22B THAP1 TNNT1 TRAF2 TRIM23 TRIM29 TRIM37 TSC22D4 YES1 ZBTB22 ZBTB8A ZMAT2 ZNF451 ZNRD2 ZSCAN1	10 interacting genes: APP CEP70 DACH1 FXR2 GOLGA2 SDCBP2 SRPK2 STAC3 TERF1 THAP1
Entrez ID		9513	79169
HPRD ID		05629	10090
Ensembl ID		ENSG00000129245	ENSG00000143793
Uniprot IDs		P51116	Q9BU76
PDB IDs		3H8Z
Enriched GO Terms of Interacting Partners?
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