FXR2 and DDX17

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		FXR2	DDX17
Description		FMR1 autosomal homolog 2	DEAD-box helicase 17
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Axon Growth Cone Ribonucleoprotein Granule Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Dendritic Spine Dendritic Spine Neck Presynapse Dendritic Filopodium	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity	Transcription Coactivator Activity RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Negative Regulation Of Translation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Positive Regulation Of Response To DNA Damage Stimulus	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II RRNA Processing RNA Processing MiRNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Gene Silencing By RNA Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Regulation Of Skeletal Muscle Cell Differentiation
Pathways			SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737) IgM levels ( 23118916) Sex hormone-binding globulin levels ( 22675492)	Menopause (age at onset) ( 26414677) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		101 interacting genes: AKAP9 AMOTL2 AP1M1 AP2M1 ARL6IP1 BAZ2B BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CAMK2D CBS CCDC33 CCDC85B CDKL3 CEP44 CEP55 COIL CYFIP1 CYFIP2 DDX17 DMRTB1 DPPA2 DYNLT1 EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GKAP1 GTSE1 HMBOX1 HNRNPC KCNRG KCTD4 KIAA1217 KIF1A KIF2A KRT20 KXD1 LASP1 LCMT1 LCP2 LDOC1 MAPRE3 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MRPL43 NCK2 NDEL1 NDN NECAB2 NIF3L1 NME1 NONO NT5C2 PAF1 PAICS PCBD1 PCM1 PIM1 POM121 PRAM1 PRC1 PSME3 PTS RABAC1 RALYL RBBP8 RBM14 RBMX RBPMS RPIA RTN3 RTN4 SCEL SNAP23 SRPK2 SYT6 SYTL4 TBC1D22B THAP1 TNNT1 TRAF2 TRIM23 TRIM29 TRIM37 TSC22D4 YES1 ZBTB22 ZBTB8A ZMAT2 ZNF451 ZNRD2 ZSCAN1	33 interacting genes: APBB1 APP BYSL CREBBP CSNK2A1 DDX5 ESR1 FBL FXR2 GRB2 HDAC1 HNRNPH3 HNRNPK LNX1 NCOA1 NCOA2 NCOA3 PIN1 PTPRD RBM10 RBM14 RBM15 RBM4 RBM5 SF1 SF3B4 SNRNP70 SORBS3 SREK1 SUMO2 WBP11 WBP2 YWHAG
Entrez ID		9513	10521
HPRD ID		05629	10532
Ensembl ID		ENSG00000129245	ENSG00000100201
Uniprot IDs		P51116	A0A1W2PQ51 Q59F66 Q92841
PDB IDs		3H8Z
Enriched GO Terms of Interacting Partners?
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