EFHC1 and CACNA1E

Number of citations of the paper that reports this interaction (PubMedID 15258581)
57

Data Source:
HPRD (in vivo, in vitro)

		EFHC1	CACNA1E
Description		EF-hand domain containing 1	calcium voltage-gated channel subunit alpha1 E
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Centrosome Axoneme Neuronal Cell Body Mitotic Spindle	Plasma Membrane Voltage-gated Calcium Channel Complex Synapse
	Molecular Function	Calcium Ion Binding Protein Binding Protein C-terminus Binding Alpha-tubulin Binding	Voltage-gated Calcium Channel Activity Calcium Ion Binding Voltage-gated Cation Channel Activity
	Biological Process	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Regulation Of Cell Division Cilium-dependent Cell Motility	Calcium Ion Transport Chemical Synaptic Transmission Regulation Of Ion Transmembrane Transport Regulation Of Insulin Secretion Membrane Depolarization Calcium Ion Import Calcium Ion Transmembrane Transport
Pathways			Presynaptic depolarization and calcium channel opening Regulation of insulin secretion
Drugs
Diseases		Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		Atopic march ( 26542096) Mean platelet volume ( 27863252) Perceived intensity of glucose ( 31005972) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Body mass index (change over time) ( 25378290) Coronary artery calcification ( 23870195) Feeling hurt ( 29500382) Height ( 31562340) Intelligence (MTAG) ( 29326435) Lumbar spine bone mineral density (integral) ( 27476799) Neuroticism ( 29255261) Presence of antiphospholipid antibodies ( 27098658)
Interacting Genes		18 interacting genes: CACNA1E DOK7 EFHC2 EIF4ENIF1 GOLGA2 HOMER3 IHO1 IKZF3 KCTD4 KRT15 REL RIMBP3 SH3GLB2 TCF4 TEX11 TRAF2 TRIP6 ZBED1	2 interacting genes: EFHC1 HSPA1A
Entrez ID		114327	777
HPRD ID		10583	03006
Ensembl ID		ENSG00000096093	ENSG00000198216
Uniprot IDs		B2CKC5 Q5JVL4	Q15878 Q59FG1
PDB IDs			3BXL
Enriched GO Terms of Interacting Partners?
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