CD27 and SIVA1

Number of citations of the paper that reports this interaction (PubMedID 9177220)
58

Data Source:
HPRD (in vitro, two hybrid)

		CD27	SIVA1
Description		CD27 molecule	SIVA1 apoptosis inducing factor
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Nucleoplasm Cytoplasm
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process	Virus Receptor Activity Tumor Necrosis Factor Receptor Binding CD27 Receptor Binding Protein Binding Metal Ion Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Immunoglobulin Mediated Immune Response Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Ethanol Positive Regulation Of B Cell Differentiation Positive Regulation Of T Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of T Cell Apoptotic Process Extrinsic Apoptotic Signaling Pathway Positive Regulation Of NIK/NF-kappaB Signaling	Viral Entry Into Host Cell Extrinsic Apoptotic Signaling Pathway
Pathways		TNFs bind their physiological receptors
Drugs			Zinc
Diseases
GWAS		Crohn's disease ( 26192919)	Endometrial cancer ( 27135401) Endometrial endometrioid carcinoma ( 27135401)
Interacting Genes		7 interacting genes: ACTN2 CD70 SIVA1 TRAF2 TRAF3 TRAF5 UHRF2	20 interacting genes: ABL2 APP BAG5 BCL2L1 BEX3 CD27 CD4 CDKN2A MEFV NEDD4 NEDD4L PCNA POLR2M PXMP2 RAD18 RHOU SSBP3 TCAP TNFRSF4 UBE2D1
Entrez ID		939	10572
HPRD ID		01723	16124
Ensembl ID		ENSG00000139193	ENSG00000184990
Uniprot IDs		P26842	O15304
PDB IDs		5TL5 5TLJ 5TLK
Enriched GO Terms of Interacting Partners?
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