SIVA1 and TNFRSF4

Number of citations of the paper that reports this interaction (PubMedID 12478477)
21

Data Source:
HPRD (in vitro)

		SIVA1	TNFRSF4
Description		SIVA1 apoptosis inducing factor	TNF receptor superfamily member 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface
	Molecular Function	Virus Receptor Activity Tumor Necrosis Factor Receptor Binding CD27 Receptor Binding Protein Binding Metal Ion Binding	Virus Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding
	Biological Process	Viral Entry Into Host Cell Extrinsic Apoptotic Signaling Pathway	Inflammatory Response Immune Response Positive Regulation Of B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway T Cell Proliferation Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell Negative Regulation Of Cytokine Secretion Positive Regulation Of Immunoglobulin Secretion
Pathways			TNFs bind their physiological receptors
Drugs		Zinc
Diseases
GWAS		Endometrial cancer ( 27135401) Endometrial endometrioid carcinoma ( 27135401)	Inflammatory bowel disease ( 23128233)
Interacting Genes		20 interacting genes: ABL2 APP BAG5 BCL2L1 BEX3 CD27 CD4 CDKN2A MEFV NEDD4 NEDD4L PCNA POLR2M PXMP2 RAD18 RHOU SSBP3 TCAP TNFRSF4 UBE2D1	10 interacting genes: NUFIP2 RC3H1 SIVA1 TNFRSF9 TNFSF4 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5
Entrez ID		10572	7293
HPRD ID		16124	02636
Ensembl ID		ENSG00000184990	ENSG00000186827
Uniprot IDs		O15304	P43489
PDB IDs			1D0A 2HEV 2HEY 6OGX 6OKM 6OKN
Enriched GO Terms of Interacting Partners?
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