SLC9A3R2 and WWTR1

Number of citations of the paper that reports this interaction (PubMedID 11118213)
238

Data Source:
HPRD (in vitro)

		SLC9A3R2	WWTR1
Description		SLC9A3 regulator 2	WW domain containing transcription regulator 1
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GO Annotations	Cellular Component	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol Nuclear Body
	Molecular Function	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Cadherin Binding Molecular Adaptor Activity	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Protein-containing Complex Assembly	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Tissue Homeostasis Negative Regulation Of Protein Phosphorylation Heart Process Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Positive Regulation Of Cell Proliferation Positive Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Stem Cell Division SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Glomerulus Development Multicellular Organism Growth Hippo Signaling Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Mesenchymal Cell Differentiation Cilium Assembly Regulation Of SMAD Protein Signal Transduction Kidney Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways			Signaling by Hippo YAP1- and WWTR1 (TAZ)-stimulated gene expression YAP1- and WWTR1 (TAZ)-stimulated gene expression SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Physiological factors RUNX2 regulates osteoblast differentiation RUNX3 regulates YAP1-mediated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878 30578418) Pulse pressure ( 30578418) Systolic blood pressure ( 27841878 30578418)	Height ( 31562340) Preeclampsia ( 23551011)
Interacting Genes		37 interacting genes: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A WWTR1	17 interacting genes: DAPK1 LATS1 LATS2 MFHAS1 NKX2-1 PAX3 PLOD2 PPP1CA RUNX1 SLC9A3R2 SUMO3 TEAD3 TEAD4 WBP2 YWHAE YWHAG YWHAZ
Entrez ID		9351	25937
HPRD ID		05946	09580
Ensembl ID		ENSG00000065054	ENSG00000018408
Uniprot IDs		Q15599	Q9GZV5
PDB IDs		2D11 2HE4 2OCS 4P0C	5N5R 5N5T 5N5W 5N75
Enriched GO Terms of Interacting Partners?
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