SLC9A3R2 and RDX

Number of citations of the paper that reports this interaction (PubMedID 12499563)
5

Data Source:
HPRD (in vitro)

		SLC9A3R2	RDX
Description		SLC9A3 regulator 2	radixin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome	Ruffle Extracellular Space Plasma Membrane Microvillus Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium T-tubule Midbody Cortical Actin Cytoskeleton Cleavage Furrow Stereocilium Cell Tip Extracellular Exosome Cell Periphery
	Molecular Function	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Cadherin Binding Molecular Adaptor Activity	RNA Binding Actin Binding Protein Binding Protein Domain Specific Binding Cadherin Binding Protein Kinase A Binding ATPase Binding
	Biological Process	Protein-containing Complex Assembly	Regulation Of Cell Shape Regulation Of Cell Size Positive Regulation Of Gene Expression Protein Kinase A Signaling Microvillus Assembly Positive Regulation Of Cell Migration Regulation Of Actin Filament Bundle Assembly Regulation Of Rap Protein Signal Transduction Negative Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of GTPase Activity Cellular Response To Platelet-derived Growth Factor Stimulus Regulation Of GTPase Activity Apical Protein Localization Establishment Of Protein Localization Negative Regulation Of Cell Size Barbed-end Actin Filament Capping Establishment Of Endothelial Barrier Protein Localization To Plasma Membrane Cellular Response To Thyroid Hormone Stimulus Regulation Of Ruffle Assembly Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Organelle Assembly Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways			Recycling pathway of L1 Recycling pathway of L1
Drugs			1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS		Diastolic blood pressure ( 27841878 30578418) Pulse pressure ( 30578418) Systolic blood pressure ( 27841878 30578418)	Cognitive function ( 24684796) Multiple sclerosis ( 31604244)
Interacting Genes		37 interacting genes: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A WWTR1	19 interacting genes: ABCC2 ARHGDIA CALM1 CPNE1 CPNE2 CPNE4 DRD3 EZR GNA13 ICAM2 ITGB2 KMT2A L1CAM ROCK1 SLC9A3R1 SLC9A3R2 TSC1 VPS11 VWA5A
Entrez ID		9351	5962
HPRD ID		05946	01534
Ensembl ID		ENSG00000065054	ENSG00000137710
Uniprot IDs		Q15599	B0YJ88 P35241 Q6PKD3
PDB IDs		2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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