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SCGB3A1 and FBXW7
Number of citations of the paper that reports this interaction (PubMedID
25640309
)
5
Data Source:
BioGRID
(two hybrid)
SCGB3A1
FBXW7
Description
secretoglobin family 3A member 1
F-box and WD repeat domain containing 7
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Extracellular Exosome
Cell
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Mitochondrion
Endoplasmic Reticulum
Golgi Apparatus
Cytosol
SCF Ubiquitin Ligase Complex
Perinuclear Region Of Cytoplasm
Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex
Molecular Function
Cytokine Activity
Protein Binding
Cyclin Binding
Protein Binding, Bridging
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Ubiquitin Binding
Phosphothreonine Residue Binding
Ubiquitin-protein Transferase Activator Activity
Biological Process
Signal Transduction
Negative Regulation Of Cell Growth
Regulation Of Cell Proliferation
Positive Regulation Of Myoblast Fusion
Protein Polyubiquitination
Vasculogenesis
Vasculature Development
Sister Chromatid Cohesion
Notch Signaling Pathway
Negative Regulation Of Gene Expression
Negative Regulation Of Triglyceride Biosynthetic Process
Regulation Of Lipid Storage
Ubiquitin Recycling
Viral Process
Protein Ubiquitination
Lung Development
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Protein Destabilization
Regulation Of Protein Localization
Regulation Of Circadian Rhythm
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Post-translational Protein Modification
Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Notch Signaling Pathway
Rhythmic Process
Protein Stabilization
Positive Regulation Of Ubiquitin-protein Transferase Activity
Lipid Homeostasis
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Cell Cycle G1/S Phase Transition
Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Regulation Of Autophagy Of Mitochondrion
Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Protein Targeting To Mitochondrion
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Hepatocyte Proliferation
Negative Regulation Of SREBP Signaling Pathway
Negative Regulation Of Osteoclast Development
Pathways
Association of TriC/CCT with target proteins during biosynthesis
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Blood protein levels (
30072576
)
Waist-to-hip ratio adjusted for BMI (additive genetic model) (
30778226
)
Interacting Genes
9 interacting genes:
AURKA
BAG4
FBXW7
FGFR4
MARCO
NOTCH3
TGFB1
TSG101
XRCC3
54 interacting genes:
AHSG
ANGPTL4
ARL6IP1
BCAS3
BEX1
BLM
CCDC6
CCNE1
CCNE2
CDC34
CEBPD
CUL1
DISC1
EBNA1BP2
EXT1
EZH2
GATA2
GATA3
GLMN
HEY1
HIPK2
HNRNPK
IL24
JUN
KLF10
KLF5
LINGO1
MAPK3
MCL1
MMS22L
MYB
MYC
MYCN
NOTCH1
NOTCH4
NPM1
PLK1
PPARGC1A
PRKN
PSEN1
PTPN11
RACK1
RFLNA
SCGB3A1
SHPRH
SKP1
SOX9
SREBF1
STOML1
STYX
SUMF2
TSC22D4
USP9X
WDR97
Entrez ID
92304
55294
HPRD ID
05932
05888
Ensembl ID
ENSG00000161055
ENSG00000109670
Uniprot IDs
Q96QR1
G0Z2K0
Q969H0
S4R3U4
PDB IDs
2OVP
2OVQ
2OVR
5IBK
5V4B
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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