MYOZ3 and FLNC

Number of citations of the paper that reports this interaction (PubMedID 11842093)
44

Data Source:
HPRD (in vivo, in vitro)

		MYOZ3	FLNC
Description		myozenin 3	filamin C
Image		No pdb structure
GO Annotations	Cellular Component	Actin Cytoskeleton Z Disc	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere
	Molecular Function	Actin Binding Protein Binding Telethonin Binding FATZ Binding	Actin Binding Protein Binding Cytoskeletal Protein Binding Ankyrin Binding
	Biological Process		Cell Junction Assembly Muscle Fiber Development
Pathways			Cell-extracellular matrix interactions
Drugs
Diseases			Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)	Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		8 interacting genes: ACTN1 ACTN2 FLNC LDB3 MAPK6 PPP3CA PPP3CB TCAP	31 interacting genes: ADRA1A ADRA1B ADRA1D CAPN3 FURIN HIPK3 HSPB2 INPPL1 KCND2 KY MAP2K4 MTDH MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2
Entrez ID		91977	2318
HPRD ID		17624	00018
Ensembl ID		ENSG00000164591	ENSG00000128591
Uniprot IDs		Q8TDC0	Q14315 Q59H94
PDB IDs			1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O 4MGX
Enriched GO Terms of Interacting Partners?
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