FLNC and MYOZ3

Number of citations of the paper that reports this interaction (PubMedID 11842093)
44

Data Source:
HPRD (in vivo, in vitro)

		FLNC	MYOZ3
Description		filamin C	myozenin 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere	Actin Cytoskeleton Z Disc
	Molecular Function	Actin Binding Protein Binding Cytoskeletal Protein Binding Ankyrin Binding	Actin Binding Protein Binding Telethonin Binding FATZ Binding
	Biological Process	Cell Junction Assembly Muscle Fiber Development
Pathways		Cell-extracellular matrix interactions
Drugs
Diseases		Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)	Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		31 interacting genes: ADRA1A ADRA1B ADRA1D CAPN3 FURIN HIPK3 HSPB2 INPPL1 KCND2 KY MAP2K4 MTDH MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2	8 interacting genes: ACTN1 ACTN2 FLNC LDB3 MAPK6 PPP3CA PPP3CB TCAP
Entrez ID		2318	91977
HPRD ID		00018	17624
Ensembl ID		ENSG00000128591	ENSG00000164591
Uniprot IDs		Q14315 Q59H94	Q8TDC0
PDB IDs		1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O 4MGX
Enriched GO Terms of Interacting Partners?
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