FLNC and SGCD

Number of citations of the paper that reports this interaction (PubMedID 10629222)
60

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		FLNC	SGCD
Description		filamin C	sarcoglycan delta
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere	Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Integral Component Of Membrane Sarcoplasmic Reticulum Sarcolemma
	Molecular Function	Actin Binding Protein Binding Cytoskeletal Protein Binding Ankyrin Binding
	Biological Process	Cell Junction Assembly Muscle Fiber Development	Muscle Organ Development Calcium-mediated Signaling Cellular Protein-containing Complex Localization Cardiac Muscle Tissue Development Cardiac Muscle Fiber Development Calcium Ion Homeostasis Heart Contraction Coronary Vasculature Morphogenesis Cardiac Muscle Cell Contraction
Pathways		Cell-extracellular matrix interactions
Drugs
Diseases		Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy	Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD) Dilated cardiomyopathy (DCM)
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)	Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Anthropometric traits ( 19260139) Daytime sleep phenotypes ( 27126917) Egg allergy ( 25710614) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Glycemic traits (pleiotropy) ( 31021400) HIV-1 viral setpoint ( 26039976) Multiple sclerosis (age of onset) ( 19010793) Obesity-related traits ( 23251661) Pulse pressure ( 30578418) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Resting-state electroencephalogram vigilance ( 29703947) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		31 interacting genes: ADRA1A ADRA1B ADRA1D CAPN3 FURIN HIPK3 HSPB2 INPPL1 KCND2 KY MAP2K4 MTDH MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2	5 interacting genes: ADA FLNC SGCA SGCB SGCG
Entrez ID		2318	6444
HPRD ID		00018	03246
Ensembl ID		ENSG00000128591	ENSG00000170624
Uniprot IDs		Q14315 Q59H94	Q92629
PDB IDs		1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O 4MGX
Enriched GO Terms of Interacting Partners?
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