YTHDC1 and SRSF2

Number of citations of the paper that reports this interaction (PubMedID 9473574)
12

Data Source:
HPRD (two hybrid, in vitro)

		YTHDC1	SRSF2
Description		YTH domain containing 1	serine and arginine rich splicing factor 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane Nuclear Speck	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol PML Body Nuclear Speck Interchromatin Granule
	Molecular Function	RNA Binding Protein Binding N6-methyladenosine-containing RNA Binding	Transcription Corepressor Activity RNA Binding Protein Kinase C Binding Protein Binding Pre-mRNA Binding
	Biological Process	MRNA Splice Site Selection MRNA Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome	Mitotic Cell Cycle Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Response To Vitamin E MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		35 interacting genes: ABL1 ADAMTS4 CFH CLK1 CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 LAMC3 LAMTOR5 LZTS2 MPRIP PLG PROSER2 RBMY1F SDCBP2 SEPTIN10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51	34 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRPK2 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2
Entrez ID		91746	6427
HPRD ID		11689	02888
Ensembl ID		ENSG00000083896	ENSG00000161547
Uniprot IDs		J3QR07 Q96MU7	A0A024R8U5 Q01130 Q53FN0
PDB IDs		2YUD 4R3H 4R3I 6RT4 6RT5 6RT6 6RT7	2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?
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