SRSF2 and SCAF11

Number of citations of the paper that reports this interaction (PubMedID 9447963)
8

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SRSF2	SCAF11
Description		serine and arginine rich splicing factor 2	SR-related CTD associated factor 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol PML Body Nuclear Speck Interchromatin Granule	Nucleoplasm Nucleolus Nuclear Body
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Kinase C Binding Protein Binding Pre-mRNA Binding	RNA Binding Protein Binding Metal Ion Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Response To Vitamin E MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Nucleic Acid-templated Transcription	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) Morning person ( 30696823) Multiple sclerosis ( 31604244) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		34 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRPK2 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2	10 interacting genes: ATXN1L PSEN1 SNRNP70 SRPK1 SRSF1 SRSF2 SRSF3 SRSF4 STAT3 U2AF2
Entrez ID		6427	9169
HPRD ID		02888	04720
Ensembl ID		ENSG00000161547	ENSG00000139218
Uniprot IDs		A0A024R8U5 Q01130 Q53FN0	Q99590
PDB IDs		2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?
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