SRSF2 and ADAP1

Number of citations of the paper that reports this interaction (PubMedID 12565890)
4

Data Source:
HPRD (in vitro)

		SRSF2	ADAP1
Description		serine and arginine rich splicing factor 2	ArfGAP with dual PH domains 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol PML Body Nuclear Speck Interchromatin Granule	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Kinase C Binding Protein Binding Pre-mRNA Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Response To Vitamin E MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Nucleic Acid-templated Transcription	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of GTPase Activity
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Nuclear signaling by ERBB4
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Diseases
GWAS
Interacting Genes		34 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRPK2 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2	23 interacting genes: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1
Entrez ID		6427	11033
HPRD ID		02888	09733
Ensembl ID		ENSG00000161547	ENSG00000105963
Uniprot IDs		A0A024R8U5 Q01130 Q53FN0	A8K3A2 B4DUZ7 O75689
PDB IDs		2KN4 2LEA 2LEB 2LEC	3FEH 3FM8 3LJU 3MDB
Enriched GO Terms of Interacting Partners?
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