YTHDC1 and KHDRBS2

Number of citations of the paper that reports this interaction (PubMedID 15345239)
21

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		YTHDC1	KHDRBS2
Description		YTH domain containing 1	KH RNA binding domain containing, signal transduction associated 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane Nuclear Speck	Nucleus Nucleoplasm
	Molecular Function	RNA Binding Protein Binding N6-methyladenosine-containing RNA Binding	RNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding Identical Protein Binding
	Biological Process	MRNA Splice Site Selection MRNA Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome	MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome
Pathways			PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)
Interacting Genes		35 interacting genes: ABL1 ADAMTS4 CFH CLK1 CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 LAMC3 LAMTOR5 LZTS2 MPRIP PLG PROSER2 RBMY1F SDCBP2 SEPTIN10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51	34 interacting genes: AEN CATSPER1 CHTOP CIRBP DOCK2 EWSR1 GRAP2 GRB2 HBZ HNRNPK HNRNPLL KHDRBS3 LINC01018 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBM10 RBM3 RBMX SDCBP SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF688
Entrez ID		91746	202559
HPRD ID		11689	13775
Ensembl ID		ENSG00000083896	ENSG00000112232
Uniprot IDs		J3QR07 Q96MU7	Q5VWX1
PDB IDs		2YUD 4R3H 4R3I 6RT4 6RT5 6RT6 6RT7
Enriched GO Terms of Interacting Partners?
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