AP1G1 and AP1B1

Number of citations of the paper that reports this interaction (PubMedID 11409905)
12

Data Source:
HPRD (two hybrid)

		AP1G1	AP1B1
Description		adaptor related protein complex 1 subunit gamma 1	adaptor related protein complex 1 subunit beta 1
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Rab GTPase Binding Kinesin Binding GTP-dependent Protein Binding	Protein Binding Protein Kinase Binding Clathrin Binding
	Biological Process	Intracellular Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Golgi To Lysosome Transport	Intracellular Protein Transport Determination Of Left/right Symmetry Heart Development Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Post bronchodilator FEV1 ( 26634245) Superior temporal sulcus banks volume ( 31530798)	Carotid atherosclerosis in HIV infection ( 20009918) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Pancreatic cancer ( 25086665)
Interacting Genes		24 interacting genes: AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CLINT1 CLTC DNER EPS15 KIF13A MAP1A PSEN2 RABEP1 RABGEF1 SPTB SYNRG SYP UBL7 UPF1 ZNF512B	22 interacting genes: AP1G1 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CLTC CREBBP KIF13A MTNR1B NTRK2 PIP5K1C PRKDC SHBG SLC2A8 SMAD2
Entrez ID		164	162
HPRD ID		04637	02541
Ensembl ID		ENSG00000166747	ENSG00000100280
Uniprot IDs		A0A140VJE7 O43747 Q8IY97	Q10567
PDB IDs		1IU1	4HMY 4P6Z 6CM9 6CRI 6D83 6D84 6DFF
Enriched GO Terms of Interacting Partners?
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