EHHADH and KCTD6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EHHADH	KCTD6
Description		enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	potassium channel tetramerization domain containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol	Cytosol M Band
	Molecular Function	3-hydroxyacyl-CoA Dehydrogenase Activity Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Enzyme Binding	Protein Binding Ankyrin Binding Identical Protein Binding Cullin Family Protein Binding
	Biological Process	Internal Protein Amino Acid Acetylation Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Growth Post-translational Protein Modification Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization
Pathways		Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import	RUNX1 regulates estrogen receptor mediated transcription Neddylation Estrogen-dependent gene expression Antigen processing: Ubiquitination & Proteasome degradation
Drugs		NADH
Diseases
GWAS		Cognitive performance ( 19734545) Major depressive disorder ( 27519822 21042317)	Hepcidin/transferrin saturation ratio ( 27846281) Systemic lupus erythematosus ( 28714469) vWF levels ( 30586737)
Interacting Genes		27 interacting genes: ACTB ACTG1 BHLHE40 CAT CBS CCDC102B DES FUNDC1 KCTD6 KCTD9 KRTAP10-7 LZTS2 MID1 NECAB2 PNMA1 SCP2 SSNA1 SSX2IP TNIP1 TPP2 TRAF1 TRIM27 TRIM41 TRIM54 TRIM55 TRIM63 ZBTB9	17 interacting genes: ACTN1 ACTN3 ANK1 C8orf33 CDC23 CTNND1 EHHADH FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 PPIG PRPF31 SDCBP ZCCHC10
Entrez ID		1962	200845
HPRD ID		06125	13769
Ensembl ID		ENSG00000113790	ENSG00000168301
Uniprot IDs		Q08426	Q8NC69
PDB IDs
Enriched GO Terms of Interacting Partners?
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