KLC4 and NECAB2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KLC4	NECAB2
Description		kinesin light chain 4	N-terminal EF-hand calcium binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Kinesin Complex Microtubule	Cytoplasm Plasma Membrane Axon Dendrite
	Molecular Function	Microtubule Motor Activity Protein Binding	Calcium Ion Binding Protein Binding A2A Adenosine Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding
	Biological Process		Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Adenosine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Localization To Membrane
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS			Body mass index (change over time) ( 25378290) Corneal astigmatism ( 29422769) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Rheumatoid arthritis ( 30891314)
Interacting Genes		26 interacting genes: ABI3 AKAP9 APP CASK CEP57L1 COIL DDX6 KATNAL1 KLC2 KPNA2 KRT13 KRT15 KRT31 MEOX2 NDEL1 NECAB2 PCM1 PDE4DIP PKP2 PRC1 RBM14 SLC16A9 TADA2A USHBP1 YWHAE YWHAZ	63 interacting genes: ADORA2A AIMP2 BEX2 BEX3 BYSL C1orf109 CAPN3 CARD9 CCDC121 CCDC146 CCDC151 CCDC153 CCDC33 CCNK CENPO CPEB2 DAXX DFFA DGCR6 DGCR6L EAF2 EHHADH EIF4E2 EMILIN1 FAM161A FANCG FXR2 GCC1 GOLGA2 GTPBP10 HAUS1 INPP1 ISCU KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 NEK6 NIP7 NOC4L NTAQ1 PCM1 POLR2C PRKAA2 PSMA1 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SSC5D TEX11 TTC25 TTR USHBP1 USP7 VTA1
Entrez ID		89953	54550
HPRD ID		13932	13263
Ensembl ID		ENSG00000137171	ENSG00000103154
Uniprot IDs		A0A024RCZ8 Q9NSK0	Q7Z6G3
PDB IDs
Enriched GO Terms of Interacting Partners?
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