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VANGL2 and DVL1
Number of citations of the paper that reports this interaction (PubMedID
12490194
)
100
Data Source:
HPRD
(in vitro)
VANGL2
DVL1
Description
VANGL planar cell polarity protein 2
dishevelled segment polarity protein 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Plasma Membrane
Cell-cell Junction
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Lateral Plasma Membrane
COPII-coated ER To Golgi Transport Vesicle
Cell Pole
Cytosol
Microtubule
Postsynaptic Density
Lateral Plasma Membrane
Clathrin-coated Vesicle
Growth Cone
Cytoplasmic Vesicle
Neuron Projection
Neuronal Cell Body
Dendritic Spine
Synapse
Schaffer Collateral - CA1 Synapse
Presynapse
Glutamatergic Synapse
Wnt Signalosome
Molecular Function
Protein Binding
Molecular_function
Frizzled Binding
Protein Binding
Beta-catenin Binding
Enzyme Binding
Protein Kinase Binding
Identical Protein Binding
Rac GTPase Binding
Biological Process
Establishment Of Planar Polarity
Neural Tube Closure
Hair Follicle Development
Heart Looping
Membranous Septum Morphogenesis
Muscular Septum Morphogenesis
Planar Cell Polarity Pathway Involved In Axis Elongation
Rho Protein Signal Transduction
Anterior/posterior Pattern Specification
Heparan Sulfate Proteoglycan Biosynthetic Process
Convergent Extension Involved In Neural Plate Elongation
Regulation Of Wnt Signaling Pathway
Glomerulus Development
Regulation Of Actin Cytoskeleton Organization
Somatic Stem Cell Population Maintenance
Cell Migration Involved In Kidney Development
Post-anal Tail Morphogenesis
Dopaminergic Neuron Axon Guidance
Serotonergic Neuron Axon Guidance
Wound Healing
Positive Regulation Of JUN Kinase Activity
Apical Protein Localization
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Somatic Stem Cell Division
Establishment Of Body Hair Planar Orientation
Digestive Tract Morphogenesis
Convergent Extension Involved In Axis Elongation
Inner Ear Receptor Cell Stereocilium Organization
Orthogonal Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis
Planar Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis
Lateral Sprouting Involved In Lung Morphogenesis
Kidney Morphogenesis
Planar Cell Polarity Pathway Involved In Heart Morphogenesis
Cochlea Morphogenesis
Establishment Of Planar Polarity Involved In Neural Tube Closure
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Planar Cell Polarity Pathway Involved In Axon Guidance
Non-motile Cilium Assembly
Regulation Of Neurotransmitter Levels
Positive Regulation Of Protein Phosphorylation
Transcription By RNA Polymerase II
Negative Regulation Of Protein Kinase Activity
Neurotransmitter Secretion
Axon Guidance
Heart Development
Neuromuscular Junction Development
Neural Tube Development
Convergent Extension Involved In Neural Plate Elongation
Cytoplasmic Microtubule Organization
Negative Regulation Of Protein Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Localization To Nucleus
Social Behavior
Protein Localization To Microtubule
Intracellular Signal Transduction
Non-canonical Wnt Signaling Pathway
Receptor Clustering
Positive Regulation Of Transcription, DNA-templated
Collateral Sprouting
Axon Extension
Dendrite Morphogenesis
Synapse Organization
Protein Stabilization
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Prepulse Inhibition
Dendritic Spine Morphogenesis
Skeletal Muscle Acetylcholine-gated Channel Clustering
Negative Regulation Of Canonical Wnt Signaling Pathway
Cochlea Morphogenesis
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Presynapse Assembly
Positive Regulation Of Neuron Projection Arborization
Regulation Of Cellular Protein Localization
Beta-catenin Destruction Complex Disassembly
Positive Regulation Of Protein Localization To Presynapse
Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
PCP/CE pathway
Asymmetric localization of PCP proteins
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
PCP/CE pathway
PCP/CE pathway
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS
Cognitive performance (
19734545
)
Multiple sclerosis (
31604244
24076602
)
Systemic lupus erythematosus (
28714469
)
Inflammatory bowel disease (
28067908
)
Ulcerative colitis (
28067908
)
Interacting Genes
5 interacting genes:
AP1M1
ARFRP1
DVL1
MAGI3
SQSTM1
35 interacting genes:
ANXA7
ARRB1
ATN1
AXIN1
BRD7
CCDC88C
CSNK1D
CSNK1E
CSNK2A1
CTNNB1
CXXC4
DAAM1
DAB2
DVL3
DYNLT1
EPS8
FRAT1
HDHD2
HECW1
LRRK2
NCK2
NEDD4
PPM1A
PSMA3
RAC1
SIPA1
SMAD1
SMAD2
SMAD3
SMAD4
SMAD7
TRIM69
USP13
VANGL1
VANGL2
Entrez ID
57216
1855
HPRD ID
02758
03220
Ensembl ID
ENSG00000162738
ENSG00000107404
Uniprot IDs
A8K4L6
Q9ULK5
O14640
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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