SAP30 and YY1

Number of citations of the paper that reports this interaction (PubMedID 12788099)
18

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SAP30	YY1
Description		Sin3A associated protein 30	YY1 transcription factor
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GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Nuclear Matrix Ino80 Complex PcG Protein Complex Ribonucleoprotein Complex
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Metal Ion Binding	Four-way Junction DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding SMAD Binding Promoter-specific Chromatin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Histone Deacetylation Skeletal Muscle Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Via Homologous Recombination Regulation Of Transcription By RNA Polymerase II RNA Localization Cellular Response To DNA Damage Stimulus Spermatogenesis Anterior/posterior Pattern Specification Response To UV-C Gene Expression Negative Regulation Of Gene Expression Protein Deubiquitination Cell Differentiation Negative Regulation Of Interferon-beta Production Cellular Response To UV Response To Prostaglandin F Positive Regulation Of Transcription By RNA Polymerase II Camera-type Eye Morphogenesis Chromosome Organization Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Interleukin-1 Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression	Activation of anterior HOX genes in hindbrain development during early embryogenesis UCH proteinases DNA Damage Recognition in GG-NER TFAP2 (AP-2) family regulates transcription of growth factors and their receptors Estrogen-dependent gene expression
Drugs
Diseases
GWAS			Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Pulse pressure ( 30224653)
Interacting Genes		26 interacting genes: BRMS1 BRMS1L CIR1 CYTOR H2AC16 H2BC21 H3-4 H4-16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395	57 interacting genes: APP ATF2 ATF6 ATF7 AURKA BAP1 BCCIP BRCA1 CDKN2A CREB1 CRKL DNMT3L E2F2 E2F3 EED EP300 FKBP1A FKBP3 GRN GTF2I HCFC1 HDAC2 HDAC3 HOXA11 INO80 KAT2B MTA2 MYC NEDD4L NFKB1 NOTCH1 NPM1 NR1H2 PPIA PSMD9 RAF1 RUVBL1 RUVBL2 RYBP SAP30 SKP2 SLC39A7 SMAD1 SMAD2 SMAD3 SMURF2 SP1 SPRY1 SREBF1 TESK1 TFCP2 TP53 TWIST1 UHRF2 YAF2 ZNF232 ZRANB2
Entrez ID		8819	7528
HPRD ID		04540	02482
Ensembl ID		ENSG00000164105	ENSG00000100811
Uniprot IDs		O75446	P25490
PDB IDs		2KDP	1UBD 1ZNM 4C5I
Enriched GO Terms of Interacting Partners?
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