YY1 and INO80

Number of citations of the paper that reports this interaction (PubMedID 18026119)
76

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology, imaging technique)

		YY1	INO80
Description		YY1 transcription factor	INO80 complex ATPase subunit
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Nuclear Matrix Ino80 Complex PcG Protein Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Spindle Microtubule Plasma Membrane Nuclear Body Ino80 Complex
	Molecular Function	Four-way Junction DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding SMAD Binding Promoter-specific Chromatin Binding	DNA Binding Actin Binding Protein Binding ATP Binding DNA-dependent ATPase Activity ATPase Activity Histone Binding Alpha-tubulin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Via Homologous Recombination Regulation Of Transcription By RNA Polymerase II RNA Localization Cellular Response To DNA Damage Stimulus Spermatogenesis Anterior/posterior Pattern Specification Response To UV-C Gene Expression Negative Regulation Of Gene Expression Protein Deubiquitination Cell Differentiation Negative Regulation Of Interferon-beta Production Cellular Response To UV Response To Prostaglandin F Positive Regulation Of Transcription By RNA Polymerase II Camera-type Eye Morphogenesis Chromosome Organization Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Interleukin-1 Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II	Mitotic Sister Chromatid Segregation Double-strand Break Repair Via Homologous Recombination DNA Repair Double-strand Break Repair Chromatin Remodeling Transcription, DNA-templated Positive Regulation Of Nuclear Cell Cycle DNA Replication Protein Deubiquitination Positive Regulation Of Cell Growth DNA Duplex Unwinding Cellular Response To UV Nucleosome Mobilization ATP-dependent Chromatin Remodeling Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription By RNA Polymerase II Spindle Assembly Cell Division UV-damage Excision Repair Cellular Response To Ionizing Radiation Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis UCH proteinases DNA Damage Recognition in GG-NER TFAP2 (AP-2) family regulates transcription of growth factors and their receptors Estrogen-dependent gene expression	UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Pulse pressure ( 30224653)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Diastolic blood pressure ( 27841878) Estimated glomerular filtration rate ( 31152163 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Macular thickness ( 30535121) Menopause (age at onset) ( 26414677) Offspring birth weight ( 31043758) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Ulcerative colitis ( 28067908)
Interacting Genes		57 interacting genes: APP ATF2 ATF6 ATF7 AURKA BAP1 BCCIP BRCA1 CDKN2A CREB1 CRKL DNMT3L E2F2 E2F3 EED EP300 FKBP1A FKBP3 GRN GTF2I HCFC1 HDAC2 HDAC3 HOXA11 INO80 KAT2B MTA2 MYC NEDD4L NFKB1 NOTCH1 NPM1 NR1H2 PPIA PSMD9 RAF1 RUVBL1 RUVBL2 RYBP SAP30 SKP2 SLC39A7 SMAD1 SMAD2 SMAD3 SMURF2 SP1 SPRY1 SREBF1 TESK1 TFCP2 TP53 TWIST1 UHRF2 YAF2 ZNF232 ZRANB2	2 interacting genes: ACTN4 YY1
Entrez ID		7528	54617
HPRD ID		02482	10024
Ensembl ID		ENSG00000100811	ENSG00000128908
Uniprot IDs		P25490	A0A024R9R7 Q9ULG1
PDB IDs		1UBD 1ZNM 4C5I	6HTS
Enriched GO Terms of Interacting Partners?
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