SAP30 and ING1

Number of citations of the paper that reports this interaction (PubMedID 11784859)
71

Data Source:
HPRD (in vitro, in vivo)

		SAP30	ING1
Description		Sin3A associated protein 30	inhibitor of growth family member 1
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GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm	Nucleus
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Metal Ion Binding	Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Histone Deacetylation Skeletal Muscle Cell Differentiation	Cell Cycle Negative Regulation Of Cell Proliferation Regulation Of Cell Death Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Erosive tooth wear (severe vs non-severe) ( 29898447)
Interacting Genes		26 interacting genes: BRMS1 BRMS1L CIR1 CYTOR H2AC16 H2BC21 H3-4 H4-16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395	28 interacting genes: BRMS1 BRMS1L COPS2 CYTOR DMAP1 EP300 ESR1 H3C14 HDAC1 HDAC2 KAT2B MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 UBC YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		8819	3621
HPRD ID		04540	03337
Ensembl ID		ENSG00000164105	ENSG00000153487
Uniprot IDs		O75446	A0A0C4DFW2 Q9UK53
PDB IDs		2KDP	2QIC
Enriched GO Terms of Interacting Partners?
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