EIF3G and MPP6

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
HPRD (two hybrid)

		EIF3G	MPP6
Description		eukaryotic translation initiation factor 3 subunit G	membrane palmitoylated protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Perinuclear Region Of Cytoplasm	Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding	Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Viral Translational Termination-reinitiation	Protein-containing Complex Assembly
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Fasting glucose change (long-term) ( 31263163) Schizophrenia ( 29483656) Urate levels in obese individuals ( 25811787)
Interacting Genes		26 interacting genes: ACD AIFM1 APP EIF3A EIF3B EIF3C EIF3D EIF3H EIF3K EIF5 EPB41 FAM9B GADD45G GOLGA2 LMNA METTL3 MPHOSPH6 MPP6 PIN1 PKN2 POT1 PRKAG1 SMN1 SNCA TK1 TRIM14	28 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A MT2P1 MTREX NDN NFKB1 PARN RPS20 SMARCA4 SNX9 THOP1
Entrez ID		8666	51678
HPRD ID		04886	09509
Ensembl ID		ENSG00000130811	ENSG00000105926
Uniprot IDs		O75821	A0A024RA25 B8ZZG1 Q9NZW5
PDB IDs		2CQ0 2MJC 5K0Y
Enriched GO Terms of Interacting Partners?
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