EIF3F and MSH4

Number of citations of the paper that reports this interaction (PubMedID 23725059)
5

Data Source:
BioGRID (pull down)

		EIF3F	MSH4
Description		eukaryotic translation initiation factor 3 subunit F	mutS homolog 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Nuclear Chromosome Synaptonemal Complex Nucleus Recombination Nodule
	Molecular Function	Translation Initiation Factor Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Translation Initiation Factor Binding	DNA Binding Protein Binding DNA-dependent ATPase Activity Mismatched DNA Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Protein Deubiquitination IRES-dependent Viral Translational Initiation	Resolution Of Meiotic Recombination Intermediates Ovarian Follicle Development Mismatch Repair Synapsis Reciprocal Meiotic Recombination Spermatogenesis Female Gamete Generation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	Meiotic recombination
Drugs		Quercetin
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depression (quantitative trait) ( 20800221)	Attention function in attention deficit hyperactive disorder ( 26174813) Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)
Interacting Genes		19 interacting genes: APP ATXN1 CDK11A CDK11B CDK19 DKC1 EEF1A1 EIF3M FBXO32 HAX1 HNRNPK HTR2A MCPH1 MSH4 MTOR PTN RPS6KB1 SHBG SMAD9	9 interacting genes: ACADM DMC1 EIF3F MLH1 MLH3 MSH5 RAD51 RPA1 VBP1
Entrez ID		8665	4438
HPRD ID		04887	03658
Ensembl ID		ENSG00000175390	ENSG00000057468
Uniprot IDs		O00303	O15457
PDB IDs		3J8B 3J8C
Enriched GO Terms of Interacting Partners?
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