EAF1 and CEP76

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EAF1	CEP76
Description		ELL associated factor 1	centrosomal protein 76
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Body Nuclear Speck ELL-EAF Complex Intracellular Membrane-bounded Organelle Intercellular Bridge	Centrosome Centriole Cytosol Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Centriole Replication Ciliary Basal Body-plasma Membrane Docking
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes		15 interacting genes: APP BEND7 CCDC33 CEP76 ELL ELL2 HOMER3 MIPOL1 PSME3 SDCBP STAC3 TFCP2 TFPT TLE5 ZBTB14	55 interacting genes: AKAP7 AKT1 BANP C22orf39 CABP5 CAPN3 CCDC92 CCNK CIR1 COIL CRYBA4 CSNK1G1 CUTC DCTD DZIP1L EAF1 EP400P1 FAM90A1 GDAP2 GFAP HSPB7 ILVBL KIAA1143 KIFBP KLHDC4 LATS1 MAGEA11 MBD3 MLH1 NHLRC2 NME5 PAICS PARD6B PIN1 PLCB1 POM121 RADIL RNF128 RPL9 SALL2 SH2D4A SINHCAF STK26 TBC1D27P THRA TOB2 TSPOAP1 TSSC4 TTC21A TUFT1 TXNDC9 WDFY3 ZBTB24 ZMAT2 ZNF85
Entrez ID		85403	79959
HPRD ID		12209	12694
Ensembl ID		ENSG00000144597	ENSG00000101624
Uniprot IDs		Q96JC9	B4DP81 Q8TAP6
PDB IDs
Enriched GO Terms of Interacting Partners?
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