CEP76 and CRYBA4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		CEP76	CRYBA4
Description		centrosomal protein 76	crystallin beta A4
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Protein-containing Complex	Cellular_component
	Molecular Function	Protein Binding	Molecular_function Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Centriole Replication Ciliary Basal Body-plasma Membrane Docking	Lens Development In Camera-type Eye Visual Perception Camera-type Eye Development
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases			Anophthalmia and microphthalmia (A/M)
GWAS
Interacting Genes		55 interacting genes: AKAP7 AKT1 BANP C22orf39 CABP5 CAPN3 CCDC92 CCNK CIR1 COIL CRYBA4 CSNK1G1 CUTC DCTD DZIP1L EAF1 EP400P1 FAM90A1 GDAP2 GFAP HSPB7 ILVBL KIAA1143 KIFBP KLHDC4 LATS1 MAGEA11 MBD3 MLH1 NHLRC2 NME5 PAICS PARD6B PIN1 PLCB1 POM121 RADIL RNF128 RPL9 SALL2 SH2D4A SINHCAF STK26 TBC1D27P THRA TOB2 TSPOAP1 TSSC4 TTC21A TUFT1 TXNDC9 WDFY3 ZBTB24 ZMAT2 ZNF85	13 interacting genes: C1orf94 CCDC33 CEP76 CRYBB1 CRYBB2 EFEMP1 FHL5 GLI1 IKZF3 MIF4GD PRR22 STX11 TRIP6
Entrez ID		79959	1413
HPRD ID		12694	00432
Ensembl ID		ENSG00000101624	ENSG00000196431
Uniprot IDs		B4DP81 Q8TAP6	A0A097PIJ6 P53673
PDB IDs			3LWK
Enriched GO Terms of Interacting Partners?
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