EAF1 and ZBTB14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EAF1	ZBTB14
Description		ELL associated factor 1	zinc finger and BTB domain containing 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Body Nuclear Speck ELL-EAF Complex Intracellular Membrane-bounded Organelle Intercellular Bridge	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome
	Molecular Function	Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter	Negative Regulation Of Transcription By RNA Polymerase II Heart Valve Development Cardiac Septum Development Negative Regulation Of Transcription, DNA-templated Coronary Vasculature Development
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Cerebral amyloid deposition (PET imaging) ( 26252872)
Interacting Genes		15 interacting genes: APP BEND7 CCDC33 CEP76 ELL ELL2 HOMER3 MIPOL1 PSME3 SDCBP STAC3 TFCP2 TFPT TLE5 ZBTB14	37 interacting genes: AP1M1 ATP5PO BAZ2B BYSL CBX8 CDK16 CDKL3 CEP19 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 NAA10 PIN1 PNKP POLR2L PRMT1 RNPS1 RPL9 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TXN2 ZBTB21 ZCCHC10 ZMAT2
Entrez ID		85403	7541
HPRD ID		12209	03674
Ensembl ID		ENSG00000144597	ENSG00000198081
Uniprot IDs		Q96JC9	B2R850 O43829
PDB IDs
Enriched GO Terms of Interacting Partners?
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