COPS3 and COPS8

Number of citations of the paper that reports this interaction (PubMedID 11337588)
231

Data Source:
HPRD (in vitro)

		COPS3	COPS8
Description		COP9 signalosome subunit 3	COP9 signalosome subunit 8
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol COP9 Signalosome	Nucleus Nucleoplasm Cytosol COP9 Signalosome Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition In Utero Embryonic Development Transcription-coupled Nucleotide-excision Repair Ubiquitin-dependent Protein Catabolic Process Signal Transduction Response To Light Stimulus Post-translational Protein Modification	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair Protein Phosphorylation Activation Of NF-kappaB-inducing Kinase Activity Negative Regulation Of Cell Proliferation COP9 Signalosome Assembly Post-translational Protein Modification
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS			Asthma ( 27611488) Body mass index ( 25673413) Lung cancer ( 28604730) Motion sickness ( 25628336) Pulse pressure ( 27841878) Systemic lupus erythematosus ( 19838195)
Interacting Genes		24 interacting genes: ARAF CEBPE COPS2 COPS4 COPS5 COPS6 COPS7A COPS8 COPS9 CSNK2A1 CSNK2B CUL5 GPS1 IKBKB IKBKG IL1RN IRF5 ITGB2 LRP2BP MCPH1 MLF1 RAF1 SOS1 TP53	16 interacting genes: COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A CUL1 CUL5 DDB1 EIF3E GPS1 ITPK1 MAPRE1 NFKBIA TP53 USHBP1
Entrez ID		8533	10920
HPRD ID		07262	16737
Ensembl ID		ENSG00000141030	ENSG00000198612
Uniprot IDs		B4DN01 Q9UNS2	A0A024R4D1 Q99627
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N	4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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