COPS3 and CEBPE

Number of citations of the paper that reports this interaction (PubMedID 15588942)
5

Data Source:
BioGRID (two hybrid)

		COPS3	CEBPE
Description		COP9 signalosome subunit 3	CCAAT enhancer binding protein epsilon
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol COP9 Signalosome	Nuclear Chromatin Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition In Utero Embryonic Development Transcription-coupled Nucleotide-excision Repair Ubiquitin-dependent Protein Catabolic Process Signal Transduction Response To Light Stimulus Post-translational Protein Modification	Phagocytosis Defense Response Macrophage Differentiation Granulocyte Differentiation Cytokine Biosynthetic Process Defense Response To Bacterium Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	Transcriptional regulation of granulopoiesis
Drugs
Diseases			Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS			Acute lymphoblastic leukemia (B-cell precursor) ( 23996088) Acute lymphoblastic leukemia (childhood) ( 29348612 22076464 23512250 19684604) Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299) B-cell acute lymphoblastic leukaemia ( 31767839) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte count ( 29403010 27863252) Monocyte percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 27863252) Sum eosinophil basophil counts ( 27863252) White blood cell count (basophil) ( 29403010 27863252 28158719)
Interacting Genes		24 interacting genes: ARAF CEBPE COPS2 COPS4 COPS5 COPS6 COPS7A COPS8 COPS9 CSNK2A1 CSNK2B CUL5 GPS1 IKBKB IKBKG IL1RN IRF5 ITGB2 LRP2BP MCPH1 MLF1 RAF1 SOS1 TP53	45 interacting genes: ALX4 ATF3 ATF4 ATF5 BATF BATF2 BATF3 CCT7 CEBPA CEBPD CEBPG COPS3 CSNK1A1L DDIT3 DENND4A E2F1 EDA2R ELOB FOS FOSL1 GATA1 GPR22 GTF2A1L IL7 JUN KDM2B LDOC1 MED16 MLLT6 MYB NELFB PIAS1 POU2F1 PSAT1 RB1 SIPA1L1 SPI1 STAT6 TAF5L TBX2 TRIB1 UBE2I ZFP2 ZMYM2 ZNF384
Entrez ID		8533	1053
HPRD ID		07262	02852
Ensembl ID		ENSG00000141030	ENSG00000092067
Uniprot IDs		B4DN01 Q9UNS2	Q15744
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N	3T92
Enriched GO Terms of Interacting Partners?
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