PKP4 and ATPAF2

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		PKP4	ATPAF2
Description		plakophilin 4	ATP synthase mitochondrial F1 complex assembly factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cornified Envelope Nucleus Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Cell Junction Desmosome Midbody Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Spindle Midzone Mitotic Spindle	Mitochondrion Cytosol Nuclear Speck
	Molecular Function	Protein Binding Cadherin Binding	Protein Binding
	Biological Process	Cell-cell Junction Assembly Cell-cell Signaling Regulation Of Cell Adhesion Keratinization Positive Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Cornification Cell-cell Adhesion	Proton-transporting ATP Synthase Complex Assembly
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Borderline personality disorder ( 28632202) Obesity-related traits ( 23251661) Restless legs syndrome ( 29029846)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		19 interacting genes: ATPAF2 CDH1 CDH2 CDH5 DSC3 DSP ERBIN GABARAP GOLGA2 LNX1 LZTS2 MINK1 OSGEP PAXIP1 PDZD2 PGAM1 PSEN1 TRIM23 UBASH3B	24 interacting genes: APP ATP5F1A ATP5F1B BEGAIN CFAP206 DDIT3 EBF1 EWSR1 IKZF3 KRT40 LNX1 LRRFIP2 LZTS2 MAGEA6 PAK5 PKP4 PRDM14 RAD54B REL RPIA SORBS2 TP53BP2 TRIM23 TRIM27
Entrez ID		8502	91647
HPRD ID		05043	10599
Ensembl ID		ENSG00000144283	ENSG00000171953
Uniprot IDs		Q99569	Q8N5M1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?