ATPAF2 and BEGAIN

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		ATPAF2	BEGAIN
Description		ATP synthase mitochondrial F1 complex assembly factor 2	brain enriched guanylate kinase associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Nuclear Speck	Cytoplasm Membrane Synapse
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Proton-transporting ATP Synthase Complex Assembly	Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Pathways			Neurexins and neuroligins
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656)	Chronotype ( 30696823) Menarche (age at onset) ( 21102462) Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: APP ATP5F1A ATP5F1B BEGAIN CFAP206 DDIT3 EBF1 EWSR1 IKZF3 KRT40 LNX1 LRRFIP2 LZTS2 MAGEA6 PAK5 PKP4 PRDM14 RAD54B REL RPIA SORBS2 TP53BP2 TRIM23 TRIM27	24 interacting genes: ABLIM1 APP ATPAF2 BAHD1 CATSPER1 DEF6 DLG1 DLG4 DTNB ENKD1 FAM107A GFI1B HGS HID1 KIAA0408 QSOX1 RBL1 RIBC2 TRIM27 USP2 ZFP64 ZNF250 ZNF417 ZNF774
Entrez ID		91647	57596
HPRD ID		10599	06459
Ensembl ID		ENSG00000171953	ENSG00000183092
Uniprot IDs		Q8N5M1	Q9BUH8
PDB IDs
Enriched GO Terms of Interacting Partners?
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