ATPAF2 and LRRFIP2

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		ATPAF2	LRRFIP2
Description		ATP synthase mitochondrial F1 complex assembly factor 2	LRR binding FLII interacting protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Nuclear Speck	Cellular_component
	Molecular Function	Protein Binding	Protein Binding LRR Domain Binding
	Biological Process	Proton-transporting ATP Synthase Complex Assembly	Regulation Of Transcription, DNA-templated Biological_process Wnt Signaling Pathway
Pathways
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656)	Autism spectrum disorder or schizophrenia ( 28540026) Subjective response to lithium treatment ( 26503763)
Interacting Genes		24 interacting genes: APP ATP5F1A ATP5F1B BEGAIN CFAP206 DDIT3 EBF1 EWSR1 IKZF3 KRT40 LNX1 LRRFIP2 LZTS2 MAGEA6 PAK5 PKP4 PRDM14 RAD54B REL RPIA SORBS2 TP53BP2 TRIM23 TRIM27	3 interacting genes: ATPAF2 DNAJC19 FLII
Entrez ID		91647	9209
HPRD ID		10599	10061
Ensembl ID		ENSG00000171953	ENSG00000093167
Uniprot IDs		Q8N5M1	Q9Y608
PDB IDs
Enriched GO Terms of Interacting Partners?
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