ATPAF2 and ATP5F1A

Number of citations of the paper that reports this interaction (PubMedID 11410595)
22

Data Source:
HPRD (two hybrid)

		ATPAF2	ATP5F1A
Description		ATP synthase mitochondrial F1 complex assembly factor 2	ATP synthase F1 subunit alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Nuclear Speck	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Plasma Membrane COP9 Signalosome Membrane Proton-transporting ATP Synthase Complex Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Extracellular Exosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding ATP Binding ATPase Activity MHC Class I Protein Binding ADP Binding Angiostatin Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Proton-transporting ATP Synthase Complex Assembly	Negative Regulation Of Endothelial Cell Proliferation Lipid Metabolic Process ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Blood Vessel Endothelial Cell Migration
Pathways			Mitochondrial protein import Formation of ATP by chemiosmotic coupling Cristae formation
Drugs			Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B PICEATANNOL N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Artenimol
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		24 interacting genes: APP ATP5F1A ATP5F1B BEGAIN CFAP206 DDIT3 EBF1 EWSR1 IKZF3 KRT40 LNX1 LRRFIP2 LZTS2 MAGEA6 PAK5 PKP4 PRDM14 RAD54B REL RPIA SORBS2 TP53BP2 TRIM23 TRIM27	16 interacting genes: ABCC1 AIMP1 APP ATP5F1C ATPAF2 CSNK2A1 HSD17B10 HSPB2 PTEN PTPRF SHBG SMARCB1 YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		91647	498
HPRD ID		10599	01258
Ensembl ID		ENSG00000171953	ENSG00000152234
Uniprot IDs		Q8N5M1	P25705 V9HW26
PDB IDs
Enriched GO Terms of Interacting Partners?
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