PPFIA1 and NDN

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		PPFIA1	NDN
Description		PTPRF interacting protein alpha 1	necdin, MAGE family member
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Axon Dendrite Protein-containing Complex Presynaptic Active Zone	Nucleoplasm Centrosome Cytosol Cell Projection Perikaryon
	Molecular Function	Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Gamma-tubulin Binding
	Biological Process	Cell-matrix Adhesion Signal Transduction Neurotransmitter Secretion Glutamate Secretion Synapse Organization Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Localization To Plasma Membrane	Neuron Migration Respiratory System Process Nervous System Development Axonal Fasciculation Central Nervous System Development Negative Regulation Of Cell Proliferation Glial Cell Migration Post-embryonic Development Cytokine-mediated Signaling Pathway Sensory Perception Of Pain Regulation Of Growth Positive Regulation Of Transcription By RNA Polymerase II Neurotrophin TRK Receptor Signaling Pathway Axon Extension Multicellular Organismal Homeostasis Genetic Imprinting
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases	Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases			Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS		Coronary artery disease ( 29212778)	Depressive symptoms (SSRI exposure interaction) ( 25649181) Plasma anti-thyroid peroxidase levels ( 29678681) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		26 interacting genes: AGTPBP1 CAGE1 CAST CCNH CEP70 DNAJC5 DTNB ERC1 ERC2 FAM161A GIT1 MBIP NCOA2 NDN PPFIA2 PPFIA3 PPFIBP1 PPFIBP2 PPP2R5D PTPRC PTPRD PTPRF PTPRS TNNT1 TXLNA YWHAG	47 interacting genes: APBB1IP ARSL BLOC1S6 CALCOCO2 CCDC136 CDR2 DTNBP1 E2F1 E2F4 EEF1AKMT1 EGFR EID1 EPAS1 FAM131C FSD2 FXR2 GKAP1 GOLGA2 HIF1A HNRNPU IFFO1 IL1A IL32 IRS4 LAX1 LPXN MIER2 MKRN2 MPP6 MYG1 NEFL NGFR NUBP1 NUCB1 NUCB2 P4HA3 PJA1 PPARGC1A PPFIA1 SERTAD3 SIRT1 SSX2IP TFIP11 TP53 U2AF1 ZBTB1 ZBTB7B
Entrez ID		8500	4692
HPRD ID		11451	03667
Ensembl ID		ENSG00000131626	ENSG00000182636
Uniprot IDs		B3KVS8 Q13136	Q99608 X5D982
PDB IDs		1N7F
Enriched GO Terms of Interacting Partners?
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